TW2 gave me a wake up call when my 4 year old Inspiron 531, with upgrades, could only handle low settings.

Anyone running the game on high or ultra? If so what type of rig would it take?

I must see Triss on High settings!

I would get a i7 System with at least 6GB of Ram and a ATI HD6970 or an NVIDIA GTX570 if I were to build a new system today.

If you play with a 1680x1050 resolution only a HD6850 or HD6870 might do the trick. But I'd go for a beefier GPU anyways in order to have more power for future games.

i'm running it on ultra. runs absolutely perfect, no slowdowns or anything. here's my rig:

Gigabyte GA-870A-UD3 Motherboard
AMD Phenom x4 965 @ 3.4GHz
4GB Kingston HyperX DDR3-1333 CL7
XFX Radeon HD 5870 1GB

The game can't use more than 2GB RAM.
I have only 3.2GB on Win7 32bit and I am running the game, browser, a download and I have 1.3GB still available. So much for the need for a lot of RAM.

Otherwise, I have an AMD Phenom II 955 quad @3.2 MHz,
GTX 460Amp 1GB (oc ex factory).

Game runs on ultra with ubersampling and motion blur disabled, everything else enabled on 30-50 fps (but I haven't gotten into the woods yet, they are supposed to slow it down somewhat). NVidia cards seem to be better off on this one. At least at the moment, new drivers might fix a lot of problems in the future. So it might be up to preference or waiting a while until things are sorted out.

Phenom II X4 940BE @ stock 3GHz and a 560 Ti OC'd to 925 on the core, running on High preset at 50-60fps without issues. Ubersampling is rape, but everything else is fine.

And here, have some Triss.

Thanks for the Feedback

I have it playable on High (less Ubersampling and SSAO) with:

Phenom II x3 720
8800 GTS 512 (factory O/C)
4GB DDR2 800
Vista 32-bit
nVidia 270.61 drivers (with 3DVision uninstalled).
1440x900 (letterboxed to 1440x810).

This rig would not do High with a larger screen.

Smoothly on High preset settings using an older comp at 1920 x 1200:

Core 2 Quad 2.83 and Nvidia GTX 295
Vista 7 x64

I can play the game on ultra with just one of my 480's with i7 920 CPU, and GPU at stock settings without major slow downs. i get some stutter once in a while but not bad at all. I think all this game needs is for nvidia and ATI to address these issues in their next WHQL driver set.

Running on a i5 750 @ stock, 16GB DDR3, win7 x64, OS on a OCZ SSD, game on an Intel 320 SSD and EVGA 460GTX 1GB with everything maxed with ubersampling off abd the game is beautiful and plays just great @ 1920x1200 with Nvidia drivers 270.61 - I'm happy.